Comply with the American Heart Association’s Life’s Simple 7 (LS7) is associated with a lower lifetime risk of developing coronary heart disease (CHD), according to a new study published in Traffic.
The LS7 recommendations were designed to focus on cardiovascular health factors that a person can change by making lifestyle changes. Recommendations encourage quitting smoking, healthier eating, exercise, weight loss, blood pressure and cholesterol control, and lowering blood sugar. More information is available here.
The study authors noted that this is the first study of its kind to report lifetime risk of coronary heart disease or years without coronary heart disease consistent with polygenic risk and adherence to LS7 recommendations in patients. white and black.
The team looked at data from 8,372 white patients and 2,314 black patients over the age of 45 who were free of CHD at baseline between 1987 and 1989. All data came from data from the ARIC (Atherosclerosis Risk in communities). Three follow-up studies were conducted between 2011 and 2013, 2016 and 2017, and 2018 and 2019.
Fifty-six percent of patients were female, and the median patient age was 54 years.
Many patients can offset their lifetime risk of coronary heart disease by nearly half if they manage their health by following LS7 recommendations, the authors found.
The overall lifetime remaining risk of coronary heart disease was 27%. This ranged from 16.6% in patients with an ideal LS7 score to 43.1% in patients with a poor LS7 score.
The authors found that the association of polygenic risk score (PRS) with lifetime risk was different by ancestry. For example, among white participants, the lifetime remaining risk ranged from 19.8% to 39.3%, depending on the increase PRS categories.